✅ Application of Ammonium Acetate

Ammonium Acetate (CH₃COONH₄) is a white crystalline powder widely used in chemical, pharmaceutical, environmental, and industrial fields. Thanks to its buffering, stabilizing, and reactive properties, ammonium acetate has diverse applications across various industries. Below are the main uses of ammonium acetate:

⭐ 1. Buffer Solution in Analytical Chemistry

Ammonium acetate is commonly used to prepare buffer solutions, especially in:

• Liquid Chromatography (LC-MS) analysis

• Capillary Electrophoresis

• Spectroscopy and titration procedures

Ammonium acetate buffers are ideal for controlling pH in the range of pH 4.5 to 6.0, providing stable conditions for sensitive analytical applications.

⭐ 2. Pharmaceuticals and Biochemistry

Ammonium acetate plays a role in the pharmaceutical industry as:

• A reagent in drug synthesis

• A buffer for biological preparations

• A protein precipitant in biochemical research

It is frequently used in formulations that require mild, volatile buffering agents which do not interfere with downstream processes.

⭐ 3. Catalyst in Organic Synthesis

In organic reactions, ammonium acetate is employed as:

• A catalyst in Knoevenagel condensation reactions

• A nitrogen source in heterocyclic compound synthesis

• A reactant for producing acetamide by thermal dehydration

These applications are widely used in laboratory and industrial organic chemistry.

⭐ 4. Textile and Dyeing Industry

Ammonium acetate is used as an additive in dyeing processes, particularly in:

• Textile printing

• Synthetic fiber dyeing

It helps regulate pH and improve dye uptake, ensuring consistent coloring.

⭐ 5. Environmental Applications

Ammonium acetate is part of certain environmental testing procedures, such as:

• Soil testing for cation-exchange capacity (CEC)

• Extracting plant-available nutrients from soils

These applications support accurate soil fertility analysis in agriculture.

⭐ 6. Electroplating Industry

In some metal finishing processes, ammonium acetate serves as a complexing agent to enhance plating quality and bath stability.

✅ Typical Dosage Reference

• In buffer solutions (LC-MS): 5–50 mM depending on the method.

• In organic synthesis: Variable based on reaction conditions, typically equimolar or catalytic amounts.

• In soil testing: Used in 1M ammonium acetate solution for extraction.

✅ Conclusion

Ammonium acetate is a multifunctional chemical used in analytical labs, pharmaceutical production, textile processing, and environmental testing. Its role as a buffering agent and catalyst makes it an essential material across a range of industries.

For high-purity ammonium acetate and reliable supply, please contact Jiangsu Khonor Chemicals Co., Limited, your global chemical partner.