Tetrasodium Pyrophosphate (TSPP) is a common phosphate additive widely used in toothpaste formulations due to its excellent chelating and dispersing properties.

✅ Functions of Tetrasodium Pyrophosphate in Toothpaste:

1. Anti-Tartar Agent
   TSPP effectively inhibits the formation of dental calculus (tartar) by chelating calcium and magnesium ions in saliva, which are responsible for plaque mineralization.

2. Stabilizer
   It helps maintain the stability of the toothpaste formula by preventing the precipitation of insoluble salts.

3. pH Buffer
   TSPP helps control the pH of toothpaste, maintaining a slightly alkaline environment, which reduces acid attack on teeth and supports oral health.

4. Improves Cleaning Performance
   By dispersing plaque and debris, TSPP enhances the overall cleaning ability of toothpaste.

✅ Typical Dosage of Tetrasodium Pyrophosphate in Toothpaste:

• 0.5% – 2% of the total formula, depending on the specific formulation and desired effect.

✅ Benefits of Using Tetrasodium Pyrophosphate in Toothpaste:

• Reduces tartar buildup

• Extends the freshness of the toothpaste

• Enhances the efficacy of fluoride and other active ingredients

• Improves product shelf life

✅ Common Toothpaste Types Containing TSPP:

• Anti-tartar toothpastes

• Whitening toothpastes

• Multi-action toothpastes

• Sensitive teeth formulations (in combination with other agents)

✅ Safety:

Tetrasodium Pyrophosphate is considered safe for use in toothpaste by international health authorities (like FDA and EFSA) within the recommended dosage limits. However, excessive use beyond regulated amounts should be avoided.